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2026
- Journal Article Moonlighting Role of Meiotic SYCP1 in Breast Cancer: A Chromatin-Bound Regulator of DNA Repair, Transcription, and Drug Resistance Science Advances DOI: 10.1126/sciadv.aea2067
- Journal Article Correction: Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity eLife DOI: 10.7554/eLife.110979
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2025
- Journal Article Synaptonemal complex assembly in yeast depends on a 2:2 Ecm11–Gmc2 heterocomplex Open Biology DOI: 10.1098/rsob.250288
- Journal Article SCEP3 initiates synapsis and implements crossover interference in Arabidopsis Nature Plants DOI: 10.1038/s41477-025-02155-x
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2024
- Journal Article Crystal structures of cables formed by the acetylated and unacetylated forms of the Schizosaccharomyces pombe tropomyosin ortholog TpmCdc8 Journal of Biological Chemistry DOI: 10.1016/j.jbc.2024.107925
- Journal Article Addendum: BRCA2 stabilises RAD51 and DMC1 nucleoprotein filaments through a conserved interaction mode Nature Communications DOI: 10.1038/s41467-024-54252-8
- Journal Article BRCA2 stabilises RAD51 and DMC1 nucleoprotein filaments through a conserved interaction mode Nature Communications DOI: 10.1038/s41467-024-52699-3
- Journal Article MEILB2-BRME1 forms a V-shaped DNA clamp upon BRCA2-binding in meiotic recombination Nature Communications DOI: 10.1038/s41467-024-50920-x
- Journal Article The crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion Communications Biology DOI: 10.1038/s42003-024-05794-6
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2023
- Journal Article SYCP1 head-to-head assembly is required for chromosome synapsis in mouse meiosis Science Advances DOI: 10.1126/sciadv.adi1562
- Preprint MEILB2-BRME1 forms a V-shaped DNA clamp upon BRCA2-binding in meiotic recombination DOI: 10.1101/2023.07.04.547728
- Preprint Crystal structure of SUN1-KASH6 reveals an asymmetric LINC complex architecture compatible with nuclear membrane insertion DOI: 10.1101/2023.06.05.543797
- Journal Article The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein Journal of Cell Biology DOI: 10.1083/jcb.202204042
- Preprint A BubR1-independent pathway for CENP-E targeting to the outer corona of kinetochores DOI: 10.1101/2023.05.10.540161
- Preprint BRCA2 stabilises RAD51 and DMC1 nucleoprotein filaments through a conserved interaction mode DOI: 10.1101/2023.11.20.567968
- Journal Article Structural maturation of SYCP1-mediated meiotic chromosome synapsis by SYCE3 Nature Structural & Molecular Biology DOI: 10.1038/s41594-022-00909-1
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2022
- Preprint Parallel recruitment pathways contribute to synaptonemal complex assembly during mammalian meiosis DOI: 10.1101/2022.04.14.488335
- Preprint The meiotic LINC complex component KASH5 is an activating adaptor for cytoplasmic dynein DOI: 10.1101/2022.04.13.488131
- Journal Article Coiled-coil structure of meiosis protein TEX12 and conformational regulation by its C-terminal tip Communications Biology DOI: 10.1038/s42003-022-03886-9
- Preprint Structural maturation of SYCP1-mediated meiotic chromosome synapsis through conformational remodelling by molecular adapter SYCE3 DOI: 10.1101/2022.03.06.483192
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2021
- Preprint Structural basis for the coiled-coil architecture of human CtIP DOI: 10.1101/2021.03.05.434060
- Journal Article SUMO is a pervasive regulator of meiosis eLife DOI: 10.7554/eLife.57720
- Journal Article A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies eLife DOI: 10.7554/eLife.60175
- Journal Article Structural basis for the coiled-coil architecture of human CtIP Open Biology DOI: 10.1098/rsob.210060
- Journal Article Centrosome dysfunction associated with somatic expression of the synaptonemal complex protein TEX12 Communications Biology DOI: 10.1038/s42003-021-02887-4
- Journal Article A prometaphase mechanism of securin destruction is essential for meiotic progression in mouse oocytes Nature Communications DOI: 10.1038/s41467-021-24554-2
- Journal Article Structural basis of meiotic chromosome synaptic elongation through hierarchical fibrous assembly of SYCE2-TEX12 Nature Structural & Molecular Biology DOI: 10.1038/s41594-021-00636-z
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2020
- Preprint Structural basis of meiotic chromosome synaptic elongation through hierarchical fibrous assembly of SYCE2-TEX12 DOI: 10.1101/2020.12.30.424799
- Preprint Helical ensembles out-perform ideal helices in Molecular Replacement DOI: 10.1101/2020.06.16.154690
- Preprint Meiotic chromosome synapsis depends on multivalent SYCE1-SIX6OS1 interactions that are disrupted in cases of human infertility DOI: 10.1101/2020.02.04.934372
- Preprint A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies DOI: 10.1101/2020.03.21.001867
- Journal Article Correction: Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity eLife DOI: 10.7554/eLife.65744
- Journal Article Helical ensembles outperform ideal helices in molecular replacement Acta Crystallographica Section D Structural Biology DOI: 10.1107/S205979832001133X
- Journal Article Meiotic chromosome synapsis depends on multivalent SYCE1-SIX6OS1 interactions that are disrupted in cases of human infertility Science Advances DOI: 10.1126/sciadv.abb1660
- Journal Article Extending the scope of coiled-coil crystal structure solution by AMPLE through improved ab initio modelling Acta Crystallographica Section D Structural Biology DOI: 10.1107/S2059798320000443
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2019
- Other Delineation of the SUMO-Modified Proteome Reveals Regulatory Functions Throughout Meiosis DOI: 10.1101/828442
- Other Synchronous chromosome segregation in mouse oocytes is ensured by biphasic securin destruction and cyclin B1-Cdk1 DOI: 10.1101/824763
- Journal Article Crossover recombination and synapsis are linked by adjacent regions within the N terminus of the Zip1 synaptonemal complex protein PLOS Genetics DOI: 10.1371/journal.pgen.1008201
- Journal Article A molecular model for self-assembly of the synaptonemal complex protein SYCE3 Journal of Biological Chemistry DOI: 10.1074/jbc.RA119.008404
- Other Obtaining tertiary protein structures by the ab-initio interpretation of small angle X-ray scattering data DOI: 10.1101/572057
- Journal Article Molecular structure of human synaptonemal complex protein SYCE1 Chromosoma DOI: 10.1007/s00412-018-00688-z
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2018
- Journal Article Structural basis of meiotic chromosome synapsis through SYCP1 self-assembly Nature Structural & Molecular Biology DOI: 10.1038/s41594-018-0078-9
- Journal Article Structural basis of meiotic telomere attachment to the nuclear envelope by MAJIN-TERB2-TERB1 Nature Communications DOI: 10.1038/s41467-018-07794-7
- Journal Article An Engineered Complement Factor H Construct for Treatment of C3 Glomerulopathy. Journal of the American Society of Nephrology : JASN DOI: 10.1681/asn.2017091006
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2017
- Journal Article Single-molecule observation of DNA compaction by meiotic protein SYCP3 eLife DOI: 10.7554/eLife.22582
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2016
- Journal Article Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity. eLife DOI: 10.7554/elife.11058
- Journal Article C14ORF39/SIX6OS1 is a constituent of the synaptonemal complex and is essential for mouse fertility Nature Communications DOI: 10.1038/ncomms13298
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2015
- Journal Article CtIP tetramer assembly is required for DNA-end resection and repair. DOI: 10.1038/nsmb.2937
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2014
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2013
- Journal Article Tcf15 primes pluripotent cells for differentiation. DOI: 10.1016/j.celrep.2013.01.017
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2012
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2010
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2008
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2007
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2006
- Journal Article A region of human BRCA2 containing multiple BRC repeats promotes RAD51-mediated strand exchange. DOI: 10.1093/nar/gkl505
- Journal Article Structural biology and bioinformatics in drug design: opportunities and challenges for target identification and lead discovery. DOI: 10.1098/rstb.2005.1800
- Journal Article Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode. DOI: 10.1016/j.dnarep.2005.11.004
- Journal Article Structural analysis and classification of native proteins from E. coli commonly co-purified by immobilised metal affinity chromatography. DOI: 10.1016/j.bbagen.2006.03.027